Specifications
Immunogen
Full length native protein (purified) corresponding to Mouse CD11a.
Target
Alternative Names
ITGAL; integrin alpha L; integrin alpha-L; alpha L integrin; lymphocyte antigen 15; CD11 antigen-like family member A; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; lymphocyte function associated
Product Background
Antigen Description
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.
Pathway
Adaptive Immune System, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
Citations
Publication ()
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COA
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