Mouse anti-CD11a Monoclonal antibody, clone IJ222 Functional Grade

Antibody Isotype

IgG1

Clone

IJ222

Species Reactivity

Human

Conjugate

Alternative Names

ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; integrin alpha-L; LFA 1; LFA-1A; LFA-1 alpha; integrin gene promoter; CD11 antigen-like family member A; lymphocyte function-associated an

Entrez Gene ID

UniProt ID

Antigen Description

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.

Pathway

Adaptive Immune System, organism-specific biosystem; CXCR3-mediated signaling events, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; HTLV-I infection, organism-specific biosystem;