Anti-IgG polyclonal antibody [R-PE] (CPBT-66022RA)
Rabbit anti-Rat IgG polyclonal antibody for FC.
Datasheet
Specifications
Host Species
Rabbit
Antibody Isotype
Polyclonal IgG
Species Reactivity
Rat, Mouse
Immunogen
Rat IgG (polyclonal)
Conjugate
R-PE
Target
Alternative Names
Ig gamma 1 chain C region; Immunoglobin heavy constant gamma 1; Immunoglobulin G; IgG; IgG heavy chain; Immunoglobulin G heavy chain
Entrez Gene ID
UniProt ID
P20760
Product Background
Pathway
Classical antibody-mediated complement activation; Complement cascade; Creation of C4 and C2 activators; FCGR activation; Fcgamma receptor (FCGR) dependent phagocytosis; Immune System; Initial triggering of complement; Innate Immune System; Regulation of actin dynamics for phagocytic cup formation; Role of phospholipids in phagocytosis;
Citations
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References
Kormelink, TG; Tekstra, J; et al. Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity. ANNALS OF THE RHEUMATIC DISEASES 69:2137-2144(2010).
Hu, J; You, WJ; et al. Construction, characterization and evaluation of the protective efficacy of the Streptococcus suis double mutant strain Delta SsPep/Delta SsPspC as a live vaccine candidate in mice. MICROBIOLOGICAL RESEARCH 170:87-94(2015).
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