Anti-INHA monoclonal antibody, clone S2

Antibody Isotype

IgG2a

Clone

S2

Species Reactivity

Human

Immunogen

Synthetic peptide: MVLHLLLFLL LTPQGGHSCQ GLELARELVL AK, corresponding to N terminal amino acids 1-32 of Human Inhibin alpha.

Conjugate

Alternative Names

INHA; inhibin, alpha; inhibin alpha chain; A-inhibin subunit;

Entrez Gene ID

UniProt ID

Antigen Description

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Pathway

Glycoprotein hormones, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Ovarian Infertility Genes, organism-specific biosystem; Peptide hormone biosynthesis, organism-specific biosystem;