Alternative Names
INHA; inhibin, alpha; inhibin alpha chain; A inhibin subunit precursor; IHA; INHA; INHA_HUMAN; Inhibin alpha chain; Inhibin alpha chain precursor; Inhibin alpha subunit; A-inhibin subunit; OTTHUMP00000065425
Antigen Description
Antigen detection, in tissues and cells, is a multi-step immunohistochemical process. The initial step binds the primary antibody to its specific epitope. After labelling the antigen with a primary antibody, a universal, affinity-purified, secondary antibody is added to bind to the primary antibody. An enzyme label is then added to bind to the secondary antibody; this detection of the bound antibody is evidenced by a colorimetric reaction. BC/R1 monoclonal antibody recognises the 32kD alpha subunit of human inhibin. Inhibin is a peptide hormone that is produced by ovarian granulose cells which inhibits the release of FSH. Inhibin alpha subunit is expressed in a wide range of human tissues outside the reproductive axis such as prostate, brain, adrenal, as well as in the granulosa cells of the ovary, Sertoli cells of the testis and various cells of the fetoplacental unit. Inhibin may be used as a differential marker for adrenocortical tumours, placenta and gestational trophoblastic lesions and sex cord stromal tumours.
COA
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