This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DCABH-3501 in a publication? Let us know and earn a reward for your research.
Kobayashi, M; Kaneko-Koike, C; et al. Genetic deletion of granzyme B does not confer resistance to the development of spontaneous diabetes in non-obese diabetic mice. CLINICAL AND EXPERIMENTAL IMMUNOLOGY 173:411-418(2013).
Hendel, A; Hsu, I; et al. Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability. LABORATORY INVESTIGATION 94:716-725(2014).
Payment methods we support:
Invoice / Purchase Order
Credit card
My Review for Anti-GZMB monoclonal antibody
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Certificate of Analysis
