Synthetic peptide: C-PRLKDKKMDAHP, corresponding to internal sequence amino acids 655-666 of Human Gelsolin
Conjugate
Unconjugated
Applications
Application Notes
WB: Use at a concentration of 0.1 - 0.3 μg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 86 kDa). Peptide ELISA: antibody detection limit dilution 1:128,000.
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Pathway
Amyloids; Apoptotic cleavage of cellular proteins; Caspase cascade in apoptosis; Coregulation of Androgen receptor activity
Citations
Publication ()
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