Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Pathway
Amyloids; Apoptotic cleavage of cellular proteins; Caspase cascade in apoptosis; Coregulation of Androgen receptor activity
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