FSHR (NP_000136, 18 a.a. ~ 120 a.a) partial recombinant protein with GST tag. The sequence is CHHRICHCSNRVFLCQESKVTEIPSDLPRNAIELRFVLTKLRVIQKGAFSGFGDLEKIEI SQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQNLP
The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
Pathway
Class A/1 (Rhodopsin-like receptors); G alpha (s) signalling events; GPCR ligand binding; GPCRs, Other
Citations
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