Anti-DNMT1 monoclonal antibody, clone 71C2331.2 [HRP] (DCABH-7629)

Mouse Anti-Human DNMT1 monoclonal for ChIP; WB; IHC-P; IHC-Fr Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
71C2331.2
Species Reactivity
Mouse, Human, Zebrafish
Immunogen
Synthetic peptide corresponding to Human Dnmt1 aa 637-650. NCBI Accession No. NP_001370Sequence: EKDDREDKENAFKR Database link: P26358
Conjugate
HRP

Applications


Application Notes
WB: 2 - 4 μg/ml; IHC-P: 1 - 2 μg/ml; IHC-Fr: 1 - 2 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
DNMT1; DNA (cytosine-5-)-methyltransferase 1; AIM; DNMT; MCMT; CXXC9
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem; One Carbon Metabolism, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem;

Citations


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References


Zhu, XH; Li, F; et al. Effects of ultraviolet B exposure on DNA methylation in patients with systemic lupus erythematosus. EXPERIMENTAL AND THERAPEUTIC MEDICINE 5:1219-1225(2013).
Kim, GD; Ni, JW; et al. Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO JOURNAL 21:4183-4195(2002).

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