Anti-DNMT1 monoclonal antibody (DCABH-2956) Knockout Validated

Rabbit anti-Human DNMT1 monoclonal antibody for WB, IHC-P, FC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS4632(3)
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to residues in Human Dnmt1 (P26358).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/250 - 1/500; Flow Cyt: 1/10 - 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
DNMT1; DNA (cytosine-5-)-methyltransferase 1; DNMT; DNA (cytosine-5)-methyltransferase 1; CXXC9; MCMT
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem; One Carbon Metabolism, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Karaca, B; Atmaca, H; et al. Combination of AT-101/cisplatin overcomes chemoresistance by inducing apoptosis and modulating epigenetics in human ovarian cancer cells. MOLECULAR BIOLOGY REPORTS 40:3925-3933(2013).
Park, BL; Kim, LH; et al. Association analyses of DNA methyltransferase-1 (DNMT1) polymorphisms with systemic lupus erythematosus. JOURNAL OF HUMAN GENETICS 49:642-646(2004).

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