Anti-DNMT1 monoclonal antibody, clone 71C2331.2 (DCABH-3227)

Mouse Anti-Human DNMT1 monoclonal for IHC-P; IHC-Fr; ChIP; FC; WB; IP

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
71C2331.2
Species Reactivity
Mouse, Rat, Human, Zebrafish
Immunogen
Synthetic peptide: EKDDREDKENAFKR, corresponding to amino acids 637-650 of Human Dnmt1
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1 - 2 μg/ml; Flow Cyt: 1/100; WB: 2 - 4 μg/ml; IP: 2μg for 106 cells.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
DNMT1; DNA (cytosine-5-)-methyltransferase 1; AIM; DNMT; MCMT; CXXC9
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Methionine degradation, organism-specific biosystem; Methionine degradation, conserved biosystem; One Carbon Metabolism, organism-specific biosystem; Regulation of retinoblastoma protein, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Yun, J; Song, SH; et al. Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers. LABORATORY INVESTIGATION 92:1033-1044(2012).
Muren, NB; Barton, JK; et al. Electrochemical Assay for the Signal-On Detection of Human DNA Methyltransferase Activity. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 135:16632-16640(2013).

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