Anti-CXCR3 MAb, Alexa Fluor® 488-Conjugated

Antibody Isotype

IgG1

Immunogen

CXCR3-transfected cells

Conjugate

Alexa Fluor 488

Application Notes

Each lot of this CXCR3 antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 μl per million cells or 5 μl per 100 μl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Alternative Names

CXCR3; chemokine (C-X-C motif) receptor 3; G protein coupled receptor 9 , GPR9; C-X-C chemokine receptor type 3; CD183; CKR L2; CMKAR3; IP10 R; MigR; CXC-R3; CXCR-3; Mig receptor; IP10 receptor; IP-10 receptor; G protein-coupled receptor 9; chemokine (C-X

Entrez Gene ID

2833

UniProt ID

P49682

Antigen Description

Human CXCR3 is a chemokine receptor that binds CXCL9, CXCL10 and CXCL11. CXCR3 is highly expressed by T lymphocytes (Th1) natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. C

Pathway

CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;