Anti-CXCR3 monoclonal antibody [Alexa Fluor® 488]

Antibody Isotype

IgG1

Clone

3I6

Species Reactivity

Mouse, Rat, Human, Rhesus monkey

Immunogen

Human CXCR3 transfectants

Conjugate

Alexa Fluor 488

Application Notes

For immunofluorescent staining, the suggested use of this reagent is 5 μl per million cells or 5 μl per 100 μl of whole blood.

Alternative Names

CXCR3; chemokine (C-X-C motif) receptor 3; G protein coupled receptor 9 , GPR9; C-X-C chemokine receptor type 3; CD183; CKR L2; CMKAR3; IP10 R; MigR; CXC-R3; CXCR-3; Mig receptor; IP10 receptor; IP-10 receptor; G protein-coupled receptor 9; chemokine (C-X

Entrez Gene ID

2833

UniProt ID

P49682

Antigen Description

Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T lymphocytes (Th1), natural killer cells (NK cells), dendrit

Pathway

CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;