Anti-BMI1 monoclonal antibody, clone 2.U.32 (DCABH-3903) Knockout Validated

Mouse Anti-Human BMI1 monoclonal for ICC/IF; FC; ChIP; WB; ICC; IP; IHC-Fr; WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2.U.32
Species Reactivity
Mouse, Rat, Rabbit, Cat, Human, Xenopus laevis, Zebrafish
Immunogen
Recombinant fragment, corresponding to amino acids 1-202 of Mouse Bmi1
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 0.65 μg/ml; Flow Cyt: 0.65 μg/ml; WB: 0.2 - 2 μg/ml; IHC-P: 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
BMI1; BMI1 proto-oncogene, polycomb ring finger; PCGF4; RNF51; FLVI2/BMI1; polycomb complex protein BMI-1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Senescence and Autophagy, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;

Citations


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References


Bardos, JI; Saurin, AJ; et al. HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and Has transcriptional repression properties. JOURNAL OF BIOLOGICAL CHEMISTRY 275:28785-28792(2000).
Noguchi, K; Shiurba, R; et al. Nuclear translocation of mouse Polycomb M33 protein in regenerating liver. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 291:508-515(2002).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Order Info: Anti-BMI1 monoclonal antibody, clone 2.U.32

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