Specifications
Immunogen
Rituximab F(ab)2
Applications
Application Notes
Suitable for PK/PD bridging ELISA.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
This antibody is specific for Rituximab. No cross reactivity with other humanized antibodies. It can be used in bridging ELISA for PK/PD assay development.
Rituximab (Rituxan) is a chimeric IgG1 monoclonal antibody. It is approved for treating conditions such as non-Hodgkin's lymphoma and rheumatoid arthritis. The drug targets the CD20 antigen on B cells, leading to their destruction and reducing abnormal B cell activity.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Legendre, P; Mouthon, L; et al. Indications of rituximab in auto-immune diseases. REVUE DE MEDECINE INTERNE 35:A10-A15(2014).
Latimer, NR; Carroll, C; et al. Rituximab in Combination with Corticosteroids for the Treatment of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A NICE Single Technology Appraisal. PHARMACOECONOMICS 32:1171-1183(2014).
COA
Certificate of Analysis
![Mouse Anti-Rituximab monoclonal antibody, clone 28C7 [Biotin] (CABT-ZB244)](https://img2.creative-diagnostics.com/productimages/CABT-ZB244_1.jpg)
![Rabbit Anti-Rituximab monoclonal antibody, clone 205E8 [Biotin] (CABT-ZB247)](https://img2.creative-diagnostics.com/productimages/CABT-ZB247_1.jpg)
