Dimeric C terminal domain consisting of amino acids 275-369 [325Trp] and amino acids 275-369 [325Arg] with C-terminal 6-His tag
Nature
Recombinant
Tag/Conjugate
His
Molecular Weight
35 kDa
Alternative Names
SLC30A8, ZnT-8, ZNT8
Purity
> 95% as determined by SDS-PAGE
Format
Liquid
Buffer
20mM Tris-HCl, pH 8.0, 200mM NaCl
Preservative
None
Storage
Store at -20°C
Introduction
Zinc transporter 8 (ZNT8) is a protein that in humans is encoded by the SLC30A8 gene. ZNT8 is a zinc transporter related to insulin secretion in humans. Certain alleles of the SLC30A8 gene may increase the risk for developing type 2 diabetes, but a loss-of-function mutation appears to greatly reduce the risk of diabetes.
Q: Could you provide the sequence of this antigen? Specifically, is the amino acid at position 325 in the sequence tryptophan (325Trp) or arginine (325Arg)?
A: We regret that the specific sequence information for this product is confidential. However, we can share that this antigen construct consists of the C-terminal cytoplasmic domain fused via a linker, incorporating both the 325Trp and 325Arg variants.
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COA
Publication 
![The purity of recombinant human Zinc transporter 8 (Insect cells) [His] >98%, determined by SDS-PAGE](https://resource.creative-diagnostics.com/diagnostics/productimages-1/DAG-ZNT8I-1.jpg)
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