Anti-SLC30A8 Polyclonal Antibody (CABT-L2081) Knockout Validated

Rabbit Anti-Human SLC30A8 (Thr263~Asp369) Polyclonal Antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment corresponding to human SLC30A8 (Thr263~Asp369)
Conjugate
Unconjugated

Applications


Application Notes
Recommended dilution: WB: 0.5-2 ug/ml; 1:500-2000
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Data Examples


Knockout Varification: Lane 1: Wild-type K562 cell lysate. Lane 2: SLC30A8 knockout K562 cell lysate. Predicted MW: 40, 35kDa, Observed MW: 35kDa
Western Blot. Sample. Human BXPC3 cell lysate.
Western Blot. Sample. Human Hela cell lysate.
Western Blot. Sample. Human K562 cell lysate.
Western Blot. Sample. Human PANC-1 cell lysate.
Western Blot. Sample. Mouse 3T3-L1 cell lysate.

Target


Alternative Names
ZNT8; Zinc Transporter 8
Entrez Gene ID
UniProt ID

Product Background


Pathway
Insulin processing; Metabolism of proteins; Metal ion SLC transporters; Peptide hormone metabolism; SLC-mediated transmembrane transport; Transmembrane transport of small molecules; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds; Zinc efflux and compartmentalization by the SLC30 family;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Vaziri-Sani, F; Oak, S; et al. ZnT8 autoantibody titers in type 1 diabetes patients decline rapidly after clinical onset. AUTOIMMUNITY 43:598-606(2010).
Brorsson, C; Vaziri-Sani, F; et al. Correlations between islet autoantibody specificity and the SLC30A8 genotype with HLA-DQB1 and metabolic control in new onset type 1 diabetes. AUTOIMMUNITY 44:107-114(2011).

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