Molecular Weight
21.5 kDa
Purity
> 95% as determined by HPLC
Storage
Stable at -80°C for 12 months
Introduction
Glypican-3 (GPC3), a member of the glypican family that attaches to the cell surface by a glycosylphosphatidylinositol anchor, is overexpressed in HCC cases and is elevated in the serum of a large proportion of patients with HCC. GPC3 expression contributes to HCC growth and metastasis.
Keywords
GPC3; Glypican 3
Citations
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Gupta, A; Sheridan, RM; et al. Multifocal Hepatic Neoplasia in 3 Children With APC Gene Mutation. AMERICAN JOURNAL OF SURGICAL PATHOLOGY 37:1058-1066(2013).
Sham, JG; Kievit, FM; et al. Glypican-3-Targeting F(ab ')2 for Zr-89 PET of Hepatocellular Carcinoma. JOURNAL OF NUCLEAR MEDICINE 55:2032-2037(2014).
COA
Certificate of Analysis
