Molecular Weight
18.8 kDa
Purity
> 95% as determined by HPLC
Storage
Stable at -80°C for 12 months
Introduction
Glypican-3 (GPC3), a member of the glypican family that attaches to the cell surface by a glycosylphosphatidylinositol anchor, is overexpressed in HCC cases and is elevated in the serum of a large proportion of patients with HCC. GPC3 expression contributes to HCC growth and metastasis.
Keywords
GPC3; Glypican 3
Citations
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Feng, MQ; Gao, W; et al. Therapeutically targeting glypican-3 via a conformation-specific single-domain antibody in hepatocellular carcinoma. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:E1083-E1091(2013).
Wang, FH; Yip, YC; et al. Diagnostic utility of glypican-3 for hepatocellular carcinoma on liver needle biopsy. JOURNAL OF CLINICAL PATHOLOGY 63:599-603(2010).
COA
Certificate of Analysis
