0.05 M MES buffer, pH 6.1, 2.0 M sodium chloride, 1.0 mg/mL heparin
Preservative
None
Storage
Store at -20°C. Avoid multiple freeze/thaw cycles
Introduction
Tryptase is the most abundant secretory granule-derived serine proteinase contained in mast cells that has been used as a marker for mast cell activation. It is involved with allergenic response and is suspected to act as a mitogen for fibroblast lines. Elevated levels of serum tryptase occur in both anaphylactic and anaphylactoid reactions, but a negative test does not exclude anaphylaxis.
Keywords
Tryptase; EC 3.4.21.59; Mast cell
Citations
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