Native Sm protein purified from bovine tissues by protein-chemical methods.
Target
RNP/Sm
Nature
Native
Alternative Names
RNP/Sm; SLE; RNP/Sm ribonucleoprotein complex
Purity
> 80%
Format
Liquid
Buffer
Neutral to slightly alkaline pH and 20% glycerol as cryoprotective agent.
Preservative
None
Storage
Store at -70°C or below. Repeated freeze/thaw cycles should avoided.
Introduction
U-small nuclear riboprotein complexes (U-snRNPs), a pivotal component of spliceosomes, are formed between small non-coding nuclear RNAs and a protein moiety. Seven different Sm proteins aggregate into a heteroheptameric protein core, which is conserved between the different U-snRNP subclasses.
Keywords
Sm antigen; Smith antigen; Systemic lupus erythematosus; SLE
Citations
Publication ()
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