Product Overview
A DNA sequence encoding the Influenza A virus (A/California/7/2009 (H1N1)) nucleoprotein (translated amino acids of EPI1383382) (Met1-Asn498) was expressed with a polyhistidine tag at the C-terminus.
Molecular Weight
53.5 kDa
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
Alternative Names
Influenzavirus A; Influenza A virus; Influenza A virus H1N1; H1N1; IAV H1N1; IAV H1N1 Nucleoprotein; IAV H1N1 NP; H1N1 NP; H1N1 Nucleoprotein
Purity
> 95 % as determined by SDS-PAGE.
Buffer
Lyophilized from sterile 20mM Tris, 500 mM NaCl, 10% Glycerol, pH 7.5
Storage
Store at -20°C to -80°C
Introduction
Influenza A viral nucleoprotein (NP) plays a critical role in virus replication and host adaptation. The influenza A virus nucleoprotein (NP) is an essential multifunctional protein that encapsidates the viral genome and functions as an adapter between the virus and the host cell machinery. NPs from all strains of influenza A viruses contain two nuclear localization signals (NLSs): a well-studied monopartite NLS1 and a less-characterized NLS2, thought to be bipartite. The nucleocapsid is a complex of the viral nucleoprotein, RNA, and several other viral proteins. The nucleoprotein forms large, RNA-bound, helical filaments and acts as a scaffold for additional viral proteins.
Keywords
Influenzavirus A; Influenza A virus; Influenza A virus H1N1; H1N1; IAV H1N1; IAV H1N1 Nucleoprotein; IAV H1N1 NP; H1N1 NP; H1N1 Nucleoprotein
Citations
Publication ()
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COA
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