Specifications
Antibody Isotype
IgG1, kappa
Applications
Application Notes
ELISA, WB, FACS, FuncS, Reference antibody
Each laboratory should determine an optimum working titer for use in its particular application.
Other applications have not been tested but use in such assays should not necessarily be excluded.
General Notes
Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer.
Target
Alternative Names
Olinvacimab; TTAC-0001; CD309; KDR; VEGFR-2; VEGFR2
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Nishimura, S; Maeno, N; et al. Human lactiferous mammary gland cells produce vascular endothelial growth factor (VEGF) and express the VEGF receptors, Flt-1 and KDR/Flk-1. CYTOKINE 18:191-198(2002).
Naiyer, AJ; Flore, O; et al. Neutralizing monoclonal antibody to human VEGFR-2 (KDR) inhibits Kaposi's sarcoma associated herpes virus (KSHV) induced angiogenesis.. BLOOD 92:704A-704A(1998).
COA
Certificate of Analysis
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