Specifications
Conjugate
Functional Grade
Images
Flow cytometry.
Flow cytometry analysis of EPC in representative stem cell grafts from NHL and MM patients. Gating on ALDH hi cells in order to define cells with stem or progenitor characteristics. EPC were subsequent defined as triple positive CD34+VEGFR2+CD133+ cells (red arrow).
Immunohistochemistry.
Immunohistochemical staining of VEGFR-2 in gastric cancer tissues. (C) VEGFR-2 (?). (D) VEGFR-2 (+). (E) VEGFR-2 (++ - +++). Magnification, ×200. VEFGR-2, VEGF receptor 2.
Tumor growth inhibition
Effects of Ramucirumab and/or Paclitaxel on cell cycle progression in gastric cancer cell lines. (a) AGS, NCI-N87 human gastric cancer cells were synchronized in the G2/M phase of the cell cycle (T0).
Target
Alternative Names
KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR
Citations
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Giatromanolaki, A; Koukourakis, MI; et al. Lactate dehydrogenase 5 expression in non-Hodgkin B-cell lymphomas is associated with hypoxia regulated proteins. LEUKEMIA & LYMPHOMA 49:2181-2186(2008).
PLATE, KH; BREIER, G; et al. VASCULAR ENDOTHELIAL GROWTH-FACTOR AND GLIOMA ANGIOGENESIS - COORDINATE INDUCTION OF VEGF RECEPTORS, DISTRIBUTION OF VEGF PROTEIN AND POSSIBLE IN-VIVO REGULATORY MECHANISMS. INTERNATIONAL JOURNAL OF CANCER 59:520-529(1994).
COA
Certificate of Analysis
