Anti-KDR monoclonal antibody (DMABT-H14109)

Mouse anti-Human KDR monoclonal antibody for WB, IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
GML-7
Species Reactivity
Human
Immunogen
Recombinant protein corresponding to full length human KDR.
Conjugate
Unconjugated

Applications


Application Notes
WB (0.5-1 μg/mL); Immunohistochemistry (Frozen sections) (1-2 μg/mL) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); vascular endothelial growth factor receptor 2; CD309; FLK1; VEGFR
Entrez Gene ID
UniProt ID

Product Background


Pathway
Angiogenesis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem;

Citations


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References


Clark, DE; Smith, SK; et al. Localization of VEGF and expression of its receptors flt and KDR in human placenta throughout pregnancy. HUMAN REPRODUCTION 11:1090-1098(1996).
Witte, L; Hicklin, DJ; et al. Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy. CANCER AND METASTASIS REVIEWS 17:155-161(1998).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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