Specifications
Immunogen
A synthetic peptide surrounding to the epitope -EYYK- with dual phosphorylation sites at Tyr1008 and Tyr1009 of JAK2 from human, mouse and rat origins.
Applications
Application Notes
WB: 0.1-1 ug/mL; ELISA: 0.01-0.1 ug/mL; IP: 2-5 ug/mL; IHC: 2-10 ug/mL
Target
Alternative Names
JAK2; Janus kinase 2
Citations
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Yamauchi, T; Kaburagi, Y; et al. Growth hormone and prolactin stimulate tyrosine phosphorylation of insulin receptor substrate-1, -2, and -3, their association with p85 phosphatidylinositol 3-kinase (PI3-kinase), and concomitantly PI3-kinase activation via JAK2 kinase. JOURNAL OF BIOLOGICAL CHEMISTRY 273:15719-15726(1998).
Mascarenhas, J; Hoffman, R; et al. Myeloproliferative Neoplasms: New Translational Therapies. MOUNT SINAI JOURNAL OF MEDICINE 77:667-683(2010).
COA
Certificate of Analysis
