Anti-JAK2 Monoclonal Antibody

Name: Anti-JAK2 (mutation R683S) Monoclonal Antibody, clone XH075
SKU: DMAB-DCC069
Rating: 5 (1 reviews)

Mouse Anti-Human JAK2 (mutation R683S) Monoclonal Antibody for ELISA, WB, IHC

Bring this labeled antibody directly to your bench!

COA

SDS

Datasheet

Specifications

Clone

XH075

Species Reactivity

Human

Immunogen

A synthetic peptide from the internal region of JAK2 which includes the mutation of R683S, human origin.

Conjugate

Unconjugated

Applications

Application Notes

ELISA: 1:1000-1:5000
WB: 1:500-1:1000

Target

Entrez Gene ID

3717

Product Background

Antigen Description

JAK2 is a non-receptor tyrosine kinase. It is a number of the Janus kinase family and has been implicated in ssignaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors. JAK2 orthologs have been identified in all mammals for which complete genome genome data are available. Mutations of JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.

Pathway

AGE/RAGE pathway; ARMS-mediated activation; Adipocytokine signaling pathway; Axon guidance;

Custom Antibody Labeling

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Citations

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Datasheet

Certificate of Analysis

Safety Data Sheet

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Pandey, A; Fernandez, MM; et al. Identification of a novel immunoreceptor tyrosine-based activation motif-containing molecule, STAM2, by mass spectrometry and its involvement in growth factor and cytokine receptor signaling pathways. JOURNAL OF BIOLOGICAL CHEMISTRY 275:38633-38639(2000).

Wheeler, TT; Broadhurst, MK; et al. Stat5 phosphorylation status and DNA-binding activity in the bovine and murine mammary glands. MOLECULAR AND CELLULAR ENDOCRINOLOGY 176:39-48(2001).

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Anti-JAK2 (mutation R683S) Monoclonal Antibody, clone XH075 (DMAB-DCC069)

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Catalog # DMAB-DCC069

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