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The minimum detectable dose of Human Complement Factor H / CFH was determined to be approximately 46.88 pg/ml. This is defined as at least three times standard deviations above the mean optical density of 10 replicates of the zero standard.
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Hyvarinen, S; Uchida, K; et al. Recognition of Malondialdehyde-modified Proteins by the C Terminus of Complement Factor H Is Mediated via the Polyanion Binding Site and Impaired by Mutations Found in Atypical Hemolytic Uremic Syndrome. JOURNAL OF BIOLOGICAL CHEMISTRY 289:4295-4306(2014).
Cameron, DJ; Yang, ZL; et al. HTRA1 variant confers similar risks to geographic atrophy and neovascular age-related macular degeneration. CELL CYCLE 6:1122-1125(2007).