Tetanus toxin is an extremely potent neurotoxin produced by the vegetative cell of Clostridium tetani in anaerobic conditions, causing tetanus. It has no known function for clostridia in the soil environment where they are normally encountered. The LD50 of this toxin has been measured to be approximately 2.5-3 ng/kg, making it second only to the related botulinum toxin (LD50 2 ng/kg) as the deadliest toxin in the world.
Antigen Description
Tetanus toxin is a potent neurotoxin produced by the anaerobic bacterium Clostridium tetani. Tetanus toxoid is prepared by formaldehyde inactivation of pure neurotoxin.
Keywords
Tetanus toxin; Clostridium tetani; Tetanospasmin
Inactivation
Formaldehyde inactivation
Citations
Publication ()
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