A synthetic peptide corresponding to a sequence at the C-terminus of human IDS(430-448aa ELCREGKNLLKHFRFRDLE).
Conjugate
Unconjugated
Applications
Application Notes
Western blot:0.1-0.5 ug/ml Immunohistochemistry(Paraffin-embedded Section): 0.5-1ug/ml Other applications have not been tested. Optimal dilutions should be determined by end users.
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.
Citations
Publication ()
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