Product Overview
Blocking/Immunizing peptide for anti-IDS antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The protein encoded by this gene belongs to the sulfatase family, is localized to the lysosome, and is involved in lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this gene are associated with the X-linked lysosomal storage disease, mucopolysaccharidosis type II, also known as Hunter syndrome. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2013]
Function
catalytic activity; hydrolase activity; iduronate-2-sulfatase activity; metal ion binding; sulfuric ester hydrolase activity;
Synonyms
IDS; iduronate 2-sulfatase; SIDS; Hunter syndrome; idursulfase; iduronate 2-sulfatase 14 kDa chain; iduronate 2-sulfatase 42 kDa chain; alpha-L-iduronate sulfate sulfatase; MPS2;
Citations
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Potter, KN; Li, Y; et al. Molecular characterization of the V(H)1-Specific variable region determinants recognized by anti-idiotypic monoclonal antibodies G6 and G8. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 50:14-20(1999).
Ramya, TNC; Weerapana, E; et al. Glycoproteomics enabled by tagging sialic acid- or galactose-terminated glycans. GLYCOBIOLOGY 23:211-221(2013).