Specifications
Applications
Application Notes
IA
Each laboratory should determine an optimum working titer for use in its particular application.
Other applications have not been tested but use in such assays should not necessarily be excluded.
Images
Immobilized human A2aR VLP at 2 µg/mL can bind DMABB-JX01,EC50=0.02547 µg/mL
In vitro blocking activity of different clones
In vitro blocking activity of clone 1B5-3D7and 3F6-9G5
Target
Product Background
Pathway
Activation of TRKA receptors, organism-specific biosystem; Adenosine P1 receptors, organismspecific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.
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Citations
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Hausler, SFM; del Barrio, IM; et al. Anti-CD39 and anti-CD73 antibodies A1 and 7G2 improve targeted therapy in ovarian cancer by blocking adenosine-dependent immune evasion. AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH 6:129-139(2014).
Lee, CF; Lai, HL; et al. The A(2A) Adenosine Receptor Is a Dual Coding Gene A NOVEL MECHANISM OF GENE USAGE AND SIGNAL TRANSDUCTION. JOURNAL OF BIOLOGICAL CHEMISTRY 289:1257-1270(2014).