Mab192 binds to main immunogenic region of human acetylcholine receptor and prevents ligand-binding. binds native but not denatured AChR with a Kd of 0.007 nM to the alpha 1 AChR subunit.
Epitope: 1-32, with partial dependence on 66-76
Suitable for BL, WB, ELISA
Isotype: Rat IgG
Clonality: Monoclonal
Multiplex assay ready: PBS only formulation, ready for custom conjugation.
Summary
Specifications
Antibody Isotype
IgG
Clone
Mab192
Species Reactivity
Human
Immunogen
Human muscle acetylcholine receptor
Conjugate
Unconjugated
Applications
Application Notes
BL WB, ELISA This antibody binds to the human muscle Acetylcholine receptor, which is a ligand-gated ion channel, transducing an action potential into the muscle cells. The antibody binds to the main immunogenic region (MIR) and prevents ligand-binding. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Citations
Publication ()
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