Mouse SCARB1 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

15 amino acids near the amino terminus of human SCARB1.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Reconstitution

Mouse peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.

Entrez Gene ID

Synonyms

SCARB1; scavenger receptor class B, member 1; CD36; Cla1; SRBI; Srb1; Cla-1; Hdlq1; SR-B1; SR-BI; Cd36l1; Hlb398; mSR-BI; AI120173; D5Ertd460e; scavenger receptor class B member 1; HDL QTL 1; scavenger receptor class B1; scavenger receptor class B type I;