Human SCNN1A blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-SCNN1A antibody

Target

SCNN1A

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]

Function

WW domain binding; actin binding; ion channel activity; ligand-gated sodium channel activity; protein binding;

Synonyms

SCNN1A; sodium channel, non-voltage-gated 1 alpha subunit; SCNN1, sodium channel, non voltage gated 1 alpha , sodium channel, nonvoltage gated 1 alpha; amiloride-sensitive sodium channel subunit alpha; ENaCalpha; alpha-ENaC; alpha-NaCH; alpha ENaC-2; epithelial Na(+) channel subunit alpha; sodium channel, nonvoltage-gated 1 alpha; nasal epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; amiloride-sensitive sodium channel subunit alpha 2; amiloride-sensitive epithelial sodium channel alpha subunit; BESC2; ENaCa; SCNEA; SCNN1; FLJ21883;