Product Overview
Sodium Channel ( Epithelial alpha ) peptide
Target
Epithelial Sodium Channel alpha
Tag/Conjugate
Unconjugated
Format
Lyophilized powder
Concentration
Lyophilized
Buffer
Reconstitute with 0.1 ml of distilled water.
Storage
Keep as concentrated solution. Store at 4℃ short term. For extended storage aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.
Antigen Description
Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
Synonyms
SCNN1A; sodium channel, nonvoltage-gated 1 alpha; amiloride-sensitive sodium channel subunit alpha; SCNEA; alpha-ENaC; alpha-NaCH; epithelial Na(+) channel subunit alpha; epithelial sodium channel alpha subunit; nonvoltage-gated sodium channel 1 subunit alpha; besc2; enaca; scnn1; ENaCalpha; alphaxENaC;
Citations
Publication ()
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