Recombinant shiga toxin-1 subunit B [His] (DAGA-984)

Shiga toxin-1 subunit B, recombinant protein from E.coli Datasheet

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Nature
Recombinant
Tag/Conjugate
His
Alternative Names
Shiga-like toxin; verotoxin; SLT1 and SLT2; Shiga Like Toxin-1
Purity
>95% by SDS-PAGE
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements
Size
100µg
Buffer
Saline and 50mM arginine, pH 7.4.
Storage
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
Antigen Description
Shiga-like toxin (verotoxin) is a toxin produced by some strains of Escherichia coli. Shiga-like toxin is named for its similarity to the AB5-type Shiga toxin produced by the bacteria Shigella dysenteriae. There are two known types-SLT1 and SLT2. The Shiga-like toxin is linked with hemolytic-uremic syndrome. Shiga-like toxin requires highly specific receptors on the cells' surface in order to attach and enter the cell. Species such as cattle, swine, and deer which do not carry these receptors may harbor toxigenic bacteria without any ill effect, dropping them in their feces, from where they may be distributed to humans. Shiga Like Toxin-1 Subunit B has nontoxic action, it is the functional region which binds to the receptor. The Shiga Like Toxin-1 Subunit B can be useful in vaccine study, antibody test and other functional research.
Keywords
Shiga-like toxin;verotoxin;SLT1 and SLT2;Shiga Like Toxin-1

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