Specifications
Immunogen
Recombinant protein corresponding to human NGFR.
Applications
Application Notes
Flow Cytometry (1:1000); Immunoprecipitation (1:200) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
nerve growth factor receptor; p75 ICD; TNFRSF16; nerve growth factor receptor (TNFR superfamily, member 16); CD271; OTTHUMP00000220319; p75NTR; low affinity nerve growth factor receptor; Low affinity neurotrophin receptor p75NTR; p75(NTR); Low-affinity ne
Product Background
Antigen Description
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.
Rat monoclonal antibody raised against recombinant NGFR.
Pathway
Axonal growth inhibition (RHOA activation), organism-specific biosystem; Axonal growth stimulation, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Ceramide signalling, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
Citations
Publication ()
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COA
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