Anti-NGFR monoclonal antibody (DMAB5531MH)

Mouse anti-Human NGFR monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
NF20.5
Species Reactivity
Human
Immunogen
Human melanoma cell line WM245.
Conjugate
Unconjugated

Target


Alternative Names
NGFR; nerve growth factor receptor; CD271; p75NTR; TNFRSF16; p75(NTR)
Entrez Gene ID
UniProt ID

Product Background


Pathway
Axonal growth inhibition (RHOA activation); Axonal growth stimulation; Cell death signalling via NRAGE; Ceramide signalling; Cytokine-cytokine receptor interaction; NADE modulates death signalling; NF-kB is activated and signals survival; NRAGE signals de

Citations


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References


Yu, J; Wiley, RG; et al. Altered NGF protein levels in different brain areas after immunolesion. JOURNAL OF NEUROSCIENCE RESEARCH 43:213-223(1996).
KASHIBA, H; SENBA, E; et al. AXONAL BLOCKADE INDUCES THE EXPRESSION OF VASOACTIVE INTESTINAL POLYPEPTIDE AND GALANIN IN RAT DORSAL-ROOT GANGLION NEURONS. BRAIN RESEARCH 577:19-28(1992).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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