Product Overview
Blocking/Immunizing peptide for anti-NGFR antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]
Function
death receptor activity; nerve growth factor binding; protein binding; receptor activity; signal transducer activity; transmembrane signaling receptor activity;
Synonyms
NGFR; nerve growth factor receptor; nerve growth factor receptor (TNFR superfamily, member 16); tumor necrosis factor receptor superfamily member 16; CD271; low affinity nerve growth factor receptor; p75NTR; TNFR superfamily; member 16; TNFRSF16; p75 ICD; NGF receptor; TNFR superfamily, member 16; low affinity neurotrophin receptor p75NTR; low-affinity nerve growth factor receptor; p75(NTR); Gp80-LNGFR;
Citations
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BRODIE, C; GELFAND, EW; et al. REGULATION OF IMMUNOGLOBULIN PRODUCTION BY NERVE GROWTH-FACTOR - COMPARISON WITH ANTI-CD40. JOURNAL OF NEUROIMMUNOLOGY 52:87-96(1994).
Schenone, A; Gill, JS; et al. Expression of high- and low-affinity neurotrophin receptors on human transformed B lymphocytes. JOURNAL OF NEUROIMMUNOLOGY 64:141-149(1996).