Anti-ATP1A3 monoclonal antibody, clone 2E3

Antibody Isotype

IgM

Clone

2E3

Species Reactivity

Human

Immunogen

ATP1A3 (-, 879 a.a. ~ 985 a.a) partial recombinant protein with GST tag.

Conjugate

Alternative Names

ATPase, Na+/K+ transporting, alpha 3 polypeptide; MGC13276; Sodium pump subunit alpha-3; OTTHUMP00000174456; Na(+)/K(+) ATPase alpha(III) subunit; Na+/K+ ATPase 3; Na(+)/K(+) ATPase alpha-3 subunit; sodium pump 3; EC 3.6.3.9; sodium-potassium-ATPase, alph

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 3 subunit.
Mouse monoclonal antibody raised against a partial recombinant ATP1A3.

Pathway

Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem