Specifications
Species Reactivity
Mouse; Rat
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human alpha 3 Sodium Potassium ATPase aa 850-950 (internal sequence). The exact sequence is proprietary.Database link: P13637
Applications
Application Notes
IP: 1/20 - 1/40; WB: 1/1000.
Target
Alternative Names
ATP1A3; ATPase, Na+/K+ transporting, alpha 3 polypeptide; dystonia 12 , DYT12; sodium/potassium-transporting ATPase subunit alpha-3; Na+/K+ ATPase 3; sodium pump subunit alpha-3; Na(+)/K(+) ATPase alpha-3 subunit; Na(+)/K(+) ATPase alpha(III) subunit; sod
Product Background
Antigen Description
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Pathway
Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem;
Citations
Publication ()
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