Specifications
Species Reactivity
Mouse; Rat; Sheep; Rabbit; Guinea pig; Cow; Dog; Human; Pig; Shark
Immunogen
Full length native protein (purified) corresponding to Dog alpha 3 Sodium Potassium ATPase. Canine cardiac microsomes.
Applications
Application Notes
Flow Cyt: 1μg/106 cells; IHC-Fr: 3 μg/ml; ICC/IF: 5 μg/ml; WB: 1 μg/ml; Inhibition Assay: 1/10.
Target
Alternative Names
ATP1A3; ATPase, Na+/K+ transporting, alpha 3 polypeptide; sodium/potassium-transporting ATPase subunit alpha-3;
Product Background
Antigen Description
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Pathway
Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; Carbohydrate digestion and absorption, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem;
Citations
Publication ()
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COA
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