Anti-IRAK1 monoclonal antibody (DMABT-H14057)

Mouse anti-Human IRAK1 monoclonal antibody for WB, IHC, IF, IP, sELISA, ELISA, RNAi Knockdown Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4B0
Species Reactivity
Human
Immunogen
IRAK1 (AAH54000, 530 a.a. ~ 693 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; IRAK-1; Pelle homolog
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IL-1 Signaling Pathway, organism-specific biosystem;

Citations


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References


Jeong, JJ; Jang, SE; et al. Mangiferin ameliorates colitis by inhibiting IRAK1 phosphorylation in NF-kappa B and MAPK pathways. EUROPEAN JOURNAL OF PHARMACOLOGY 740:652-661(2014).
Bhaumik, D; Scott, GK; et al. MicroRNAs miR-146a/b negatively modulate the senescence associated inflammatory mediators IL-6 and IL-8. AGING-US 1:402-411(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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