Human PKM2(Pyruvate kinase isozymes M1/M2) ELISA Kit

Geometric errors, vibration, and elastic deformation are the main causes for inaccuracy of parallel kinematic machines (PKMs). Instead of tackling these inaccuracies after the prototype has been built, this paper proposes a design optimization method to minimize vibration and deformation considering the effects of geometric errors before constructing the PKM. In this paper, geometric errors are described as parameter uncertainty because they are unknown in design stage. A five degree-of-freedom (DoF) PKM is taken to exemplify this method. Elastodynamic model is first formulated by a step-by-step strategy. On this basis, dynamic performances, including natural frequency, elastic deformation, and maximum stress, are analyzed. These analytical results are verified by finite-element simulation and experiment. Then, the necessity of concerning parameter uncertainty in optimization is addressed. Next, parameter uncertainty is added to the formulation of objectives and constraints by Monte Carlo simulation and response surface method. Finally, elastodynamic optimization of the 5-DoF PKM is implemented to rebuild a prototype which is robust to geometric errors and has minimal vibration and deformation. The proposed method can also be applied to accuracy improvement of any machines in practical applications.

Integrating the persuasion knowledge model (PKM) and privacy calculus model (PCM), this study examines how adolescents' persuasion knowledge and benefit-risk assessment of social media newsfeed advertising (SMNA) influences their coping responses. An online survey of 305 Facebook users aged 13 or older in the U.S. shows that adolescents' persuasion knowledge of SMNA has a positive impact on their benefit assessment (message relevance), but not on risk assessment (privacy risk). Furthermore, adolescents' benefit-risk assessment has an effect on their scepticism toward SMNA, which in turn leads to information disclosure on Facebook. Theoretical and managerial implications of the findings and directions for future research are discussed.