Anti-GUCY1B3 monoclonal antibody (DMAB1506MH)

Mouse anti-Human GUCY1B3 monoclonal antibody for ELISA, WB Datasheet

Online Inquiry Add to basket

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
C246M
Species Reactivity
Human
Immunogen
Recombinant human soluble Guanylate Cyclase alpha 1 beta 1 heterodimer
Conjugate
Unconjugated

Target


Alternative Names
GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Guanylate cyclase soluble subunit beta-1 is an enzyme that in humans is encoded by the GUCY1B3 gene. Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs. Suitable for use in ELISA and Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. The function about GUCY1B3 antigen include GTP binding, guanylate cyclase activity, heme binding, Hsp90 protein binding, ion binding, lyase activity, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity, protein heterodimerization activity, receptor activity.
Pathway
Formation of Platelet plug; Gap junction; Hemostasis; Long-term depression; Nitric oxide stimulates guanylate cyclase; Platelet Activation; Platelet homeostasis; Purine metabolism; Salivary secretion; Vascular smooth muscle contraction.

Citations


Have you cited DMAB1506MH in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-GUCY1B3 monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket