Anti-GUCY1B3 monoclonal antibody (DMAB1506MH)

Mouse anti-Human GUCY1B3 monoclonal antibody for ELISA, WB Datasheet

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Host Species
Antibody Isotype
Species Reactivity
Recombinant human soluble Guanylate Cyclase alpha 1 beta 1 heterodimer


Alternative Names
GUCB3; GC-SB3; GUC1B3; GUCSB3; GUCY1B1; GC-S-beta-1
Entrez Gene ID
UniProt ID

Product Background

Antigen Description
Guanylate cyclase soluble subunit beta-1 is an enzyme that in humans is encoded by the GUCY1B3 gene. Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs. Suitable for use in ELISA and Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. The function about GUCY1B3 antigen include GTP binding, guanylate cyclase activity, heme binding, Hsp90 protein binding, ion binding, lyase activity, metal ion binding, nucleotide binding, phosphorus-oxygen lyase activity, protein heterodimerization activity, receptor activity.
Formation of Platelet plug; Gap junction; Hemostasis; Long-term depression; Nitric oxide stimulates guanylate cyclase; Platelet Activation; Platelet homeostasis; Purine metabolism; Salivary secretion; Vascular smooth muscle contraction.


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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