Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide corresponding to residues in Human Guanylyl Cyclase beta 1 (Uniprot: Q02153)
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/100 - 1/250.
Target
Alternative Names
GUCY1B3; guanylate cyclase 1, soluble, beta 3; GUC1B3; guanylate cyclase soluble subunit beta-1; GC S beta 1; GC SB3; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3; GUCB3; GC-SB3; GUCSB3; GUCY1B1
Product Background
Antigen Description
Guanylate cyclase soluble subunit beta-1 is an enzyme that in humans is encoded by the GUCY1B3 gene. Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs
Pathway
Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; Hemostasis, organism-specific biosystem; Long-term depression, organism-specific biosystem; Long-term depression, conserved biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem;
Citations
Publication ()
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COA
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