DENV NS1 (full length Type-2 immunodominant regions) [His] (DAGA-249)

DENV NS1 (full length Type-2 immunodominant regions) [His], recombinant protein from E.coli

Product Overview
The E.Coli derived recombinant protein contains the NS1 Dengue Virus full length Type-2 immunodominant regions, having an Mw of 45kDa. The dengue protein is fused to 6xHis tag at C-terminus and purified by proprietary chromatographic technique.
Nature
Recombinant
Tag/Conjugate
His
Alternative Names
Dengue Virus 1+2+3+4; Dengue Virus Type 1, 2, 3, 4; Group IV; Flaviviridae; Flavivirus; Dengue virus
Procedure
1mM EDTA
Purity
Protein is>95% pure as determined by 10% SDS-PAGE (coomassie staining).
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements.
Size
100, 500, 1000 μg
Buffer
PBS, 25mM arginine and 1mM EDTA
Preservative
None
Storage
Stable at 4°C for 1 week, but should be stored below -18°C. Please prevent freeze thaw cycles.
Introduction
Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
Antigen Description
NS1 is essential for viral viability but its precise biological function is unknown. Antibodies raised in response to NS1 in viral infection can cross react with cell surface antigens on epithelial cells and platelets and this has been implicated in the d
Keywords
Dengue Virus 1+2+3+4;Dengue Virus Type 1, 2, 3, 4;Group IV;Flaviviridae;Flavivirus;Dengue virus;Dengue Virus;DENV

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Palomar, Quentin, et al. "Impedimetric quantification of anti-dengue antibodies using functional carbon nanotube deposits validated with blood plasma assays." Electrochimica Acta 274 (2018): 84-90.

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