Product Overview
Blocking/Immunizing peptide for anti-Connexin 43/GJA1 antibody
Target
Connexin 43 / GJA1
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]
Function
PDZ domain binding; SH3 domain binding; connexin binding; gap junction channel activity; ion transmembrane transporter activity; protein binding; signal transducer activity;
Synonyms
GJA1; gap junction protein, alpha 1, 43kDa; HSS; CMDR; CX43; GJAL; ODDD; AVSD3; HLHS1; DFNB38; gap junction alpha-1 protein; connexin 43; connexin-43; gap junction 43 kDa heart protein;
Citations
Publication ()
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